Compounded Semaglutide Injection

Semaglutide targets only GLP-1 receptors, while tirzepatide is a dual GLP-1/GIP receptor agonist. Tirzepatide produces slightly more weight loss in trials (22.5% vs 14.9%), but semaglutide has a longer track record and more real-world data. Both are highly effective - semaglutide is often preferred as a first-line treatment due to its established safety profile and lower starting cost.

Because we don't want our pricing model to put your doctor on the wrong side of your treatment. Most telehealth providers charge more as your dose goes up, which quietly turns every titration call into a revenue decision. We don't want our doctors anywhere near that math. One flat price means your doctor recommends exactly the dose that's clinically right for you. At 0.25mg or 2.4mg, your price is the same. Every dose also includes L-Carnitine at no extra charge.

New patients typically start at 0.25mg per week for about 4 weeks to build tolerance. From there the steps are 0.5mg, 1mg, 1.7mg, and up to 2.4mg maximum. Increases are not automatic: your dose stays the same until you tell us you're ready, then your care team reviews and approves the step up (typically no sooner than every 4 weeks). Most patients stabilize at 1mg, and only about 20% need doses above 1mg. There's no rush, and no upcharge at any dose.

Yes. You don't need to restart titration. During your consult, share your current dose and how long you've been on it (a recent prescription label or invoice helps). Your MadeMed doctor will review your history and, if appropriate, continue you at your current dose so your progress isn't interrupted. If your records show you tolerated a higher dose elsewhere, your doctor can pick up where you left off.

Most switchers go from consult to delivered medication in 5-7 business days. We ship overnight in temperature-controlled packaging once your prescription is approved. If you're running low on your current supply, mention it during the consult and we'll prioritize your shipment so you don't have a gap.

Not required, but it speeds things up. If you have a recent prescription label, pharmacy invoice, or note from your previous provider, share it during the consult. It helps your MadeMed doctor confirm your dose history and continue your treatment without restarting titration. If you don't have records, your doctor will work with you based on what you can recall about your current dose and how long you've been on it.

Never. We email you 7 days before every charge with the exact amount and easy options to pause, skip, or cancel. No surprises, no ambush billing. You're always in control of your subscription.

One click from your dashboard. No phone calls, no chat queues, no guilt trips. We believe if you want to leave, you should be able to - easily. That said, we hope you'll stay because we've earned your trust, not because we've trapped you.

Billing stops immediately. Not 'next cycle' - immediately. If you pause mid-month, you won't be charged again until you unpause. We'll send you a reminder after your pause period ends, and you can extend it anytime.

L-Carnitine is a naturally occurring amino acid derivative your body uses to shuttle fat into your cells' mitochondria, where it gets burned for energy. On a GLP-1, your appetite drops fast, which often means lower energy and more fatigue while your body adjusts. L-Carnitine helps offset that: it supports steadier energy, encourages your body to burn fat (not muscle) for fuel, and tends to reduce nausea and grogginess that some patients get in the first weeks. Most telehealth providers either don't include it, or charge extra. We add it to every dose of our semaglutide at no extra charge.

Yes. Every order ships overnight in temperature-controlled packaging at no extra cost. Medication, syringes, alcohol swabs, and injection supplies are all included.

Absolutely. Phone, email, or chat - your choice. No AI chatbots, no endless hold music. Real humans who can actually help.

Yes. You can opt in to receive personalized meal plans, recipes, shopping lists, and exercise programs tailored to your goals, dietary preferences, and progress. They're included with your plan at no extra cost.

Most patients see reduced appetite within 1-2 weeks. Noticeable weight loss (5-8% body weight) typically occurs within the first 4-8 weeks. Peak results occur at 48-72 weeks, with an average of 15-20% total body weight loss at the maximum dose. When you're ready, you and your doctor can step your dose up (typically no sooner than every 4 weeks) to optimize results while minimizing side effects.

The most common side effects are nausea, diarrhea, and decreased appetite (which is therapeutic). These are typically mild and subside within 1-2 weeks as your body adjusts. Our L-Carnitine enhancement helps reduce nausea and fatigue. Serious side effects are rare but include pancreatitis and gallbladder issues. Your doctor will monitor you throughout treatment.

It's very easy! You inject once weekly into your abdomen, thigh, or upper arm using a small insulin syringe. The injection takes about 30 seconds. We provide detailed instructions, video tutorials, and all supplies (syringes, alcohol swabs). Most patients are comfortable self-injecting after their first dose.

Weight regain is common after stopping GLP-1 medications. Your appetite will return to baseline, and you may regain some or all of the weight lost. However, many patients maintain results by transitioning to lifestyle changes developed during treatment. Some patients stay on a maintenance dose long-term to prevent regain.

Semaglutide is appropriate for adults with BMI ≥30, or BMI ≥27 with a weight-related health condition (diabetes, high blood pressure, high cholesterol). You should not take semaglutide if you have a personal or family history of medullary thyroid cancer, Multiple Endocrine Neoplasia syndrome type 2, or are pregnant/breastfeeding. Our doctors will review your medical history to determine if you're a good candidate.

Our semaglutide is compounded (not brand name Ozempic/Wegovy), so insurance typically doesn't cover it. However, our pricing is often cheaper than insurance copays for brand name versions and significantly cheaper than paying out-of-pocket for brand name ($1,000-$1,400/month). Plus, we include L-Carnitine with every dose at no extra charge.

Treatment duration varies by individual. Most patients take semaglutide for 12-18 months to reach their goal weight. Some continue on a maintenance dose long-term to prevent weight regain. Your doctor will work with you to determine the right duration based on your goals, progress, and health status.